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#1
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04-09-2019, 04:04 AM
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Lab Produces First Gene-edited Lizards
Although they're commonly known as brown anoles, there are now four Anolis sagrei lizards at a University of Georgia lab that are actually a pale pink color. They're albinos, and are the result of what is reportedly the world's first successful attempt at producing a genetically modified reptile. The research could have implications for human medicine. Lead scientist Douglas Menke chose brown anoles for the study because isolated populations of the lizards are known for independently evolving distinctive traits, on various islands in the Caribbean. Genetically modifying reptiles of any type does pose some challenges, however. Ordinarily, when utilizing the CRISPR gene-editing tool, scientists inject gene-editing solutions into an animal's freshly-fertilized egg, or into a single-cell embryo. This causes a mutation in the DNA, which gets reproduced in all of the subsequently-developed cells. In reptiles, though, females are capable of storing sperm in their oviducts for a long time after mating – this makes it hard to determine when fertilization of the egg has actually occurred. Additionally, once an egg has been fertilized, its pliable shell and lack of an internal air space make it difficult to manipulate the embryo without damaging it. In order to get around these challenges, Menke and colleagues used the CRISPR-Cas9 tool to micro-inject CRISPR proteins into immature eggs (aka oocytes) which were still located in the anoles' ovaries. They then simply waited for those eggs to be naturally fertilized. All told, the scientists injected 146 eggs in 21 of the reptiles, targeting the tyrosinase gene – when this gene is inactivated, albinism results. After a few weeks, the end result was the four pink lizards. read more: https://newatlas.com/genetically-edited-lizards/59161/ |
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#3
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04-09-2019, 04:18 PM
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Re: Lab Produces First Gene-edited Lizards
Chinese geneticists have already started CCR5 gene editing experiments on human embryos. Harvard University has also begun gene-editing human sperm. There's no use in trying to ban this sort of science out of moral panic. I'd much rather countries with higher ethical standards than places like China be at the forefront of these kinds of revolutionary technologies.
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#4
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07-13-2019, 08:16 PM
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Re: Lab Produces First Gene-edited Lizards
..... Green Logic? Why not perhaps identify 'the genome/specific gene.' I'm aware of this. In my 'purest sadness.' I saw and walked, and felt. One 'specifically punky' hat is totally free from disease and not modified, or in any way sanded or lived ... a full a.n.d. and that he was a devil. I must be most beautiful, unfulfilled or saddened watching his life. Or, any pre case/illness or disease. If I were a member of the so called, secret, perhaps fabricated, top families in this world, I would sadly be mercilessly 'PURE!' |