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#13
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08-31-2014, 05:23 AM
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Re: Cool Cold Water Extraction (Removing Paracetamol from Co-Codamol)(Tylenol)
I used to work at a doctor's office, so I was the thug who helped deal with drug-seekers/doctor-shoppers/prescription-sellers/etc. But those days are long gone. It's good to disseminate this CWE info to help reduce the damage done to your liver by paracetamol (aka APAP or "acetaminophen"). If you're going to recreate with any opiate/opioid that is combined with APAP, CWE will help reduce liver damage by getting rid of the majority of it. As for me, I only take hydros if/when I have surgery. Weed's my drug of choice, but to each their own. Have fun safely out there, you crazy opiophiles. |
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#14
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08-31-2014, 08:56 AM
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Re: Cool Cold Water Extraction (Removing Paracetamol from Co-Codamol)(Tylenol)
I mean I often get codeine without APAP and I get tramadol which have no APAP but sometimes I get these and my liver has taken a real pounding over the years so like you say and damage reduction is a good thing |
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#15
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09-09-2014, 05:37 PM
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Re: Cool Cold Water Extraction (Removing Paracetamol from Co-Codamol)(Tylenol)
It should be pointed out that the final product is not completely free of paracetamol (acetaminophenol). Paracetamol is soluble in water to some extent, just far less so than codeine, so some will pass through the coffee filter as it is dissolved. Also some particles will be small enough to pass through the coffee filter anyway. As a rough guideline, when I have performed this in the past I worked on the assumption that 20 % of the paracetamol will be present in the final product. This is a definite exaggeration, but intended to keep things well within the margins of safety. However it does mean if you want to play safe with this method you shouldn't be banging more than 10 tablets into the mix if they contain 500mg paracetamol. Guidelines vary, but in most of Europe the maximum dose to take at any one time is 1000mg. There are methods you can use to beef up the odds more in your favour. Knowing the solubility of the component drugs helps. Here is a rough guide - Drug Solubility at 31 Celsius Solubility at 21 Celsius Aspirin 1 gram / 100ml 1 gram / 300ml Paracetamol 1 gram / 70ml 1 gram / 150ml Codeine 1 gram / 2.3ml 1 gram / 0.7ml The above figures apply when water is used as the solvent. As can be seen, paracetamol needs 150 ml water to dissolve a gram at 21 degrees (room temperature) Any more paracetamol will fail to dissolve in the solution. Therefore you could theoretically take 20 tablets that contain a paracetamol to codeine ratio of 500mg / 8mg and dissolve them into water. This can even be done at high temperature if desired because we can cool this down thereby manipulating the saturation point of the solution. Once the liquid cools, the paracetamol that dissolved at high temperature will precipitate out and the solution can only contain 1 gram paracetamol when it reaches room temperature again. It will of course contain invisibly small particles of paracetamol floating in suspension, which is where the next stage comes into effect. The filtering ought to be done at least three times and ideally with filter paper suitable for laboratory use, but a double paper coffee filter is almost as good. With this method you can achieve a solution that contains 1 gram paracetamol and 160 mg codeine. You will lose 10 % of this to the filter paper and 10 % to error or solubility differences in various water samples so even with the calculations based on worst case scenario, you should end up with 130 mg codeine and 990 mg paracetamol. This is a classed as a high dose of codeine, but is nowhere near approaching a dose considered to be dangerous. Doctors prescribe it regularly at doses up to 120 mg. |