[Faline]

The main characteristics of Waardenburg syndrome (WS) include: a wide bridge of the nose; pigmentary disturbances such as two different colored eyes, white forelock and eyelashes and premature graying of the hair; and some degree of cochlear deafness. The disease was named for Petrus Johannes Waardenburg, a Dutch ophthalmologist (1886-1979) who was the first to notice that people with two different colored eyes frequently had hearing problems.

The several types of WS are inherited in dominant fashion, so researchers typically see families with several generations who have inherited one or more of the features.Type I of the disorder is characterized by displacement of the fold of the eyelid, while Type II does not include this feature, but instead has a higher frequency of deafness.

The discovery of the human gene that causes Type I WS came about after scientists speculated that the gene that causes 'splotch mice' (mice with a splotchy coat coloring) might be the same gene that causes WS in humans. They located the human gene to chromosome 2 and found it was the same as mouse Pax3. Pax3 is one of a family of eight mouse Pax genes that are involved in regulating embryonic development at the level of transcription.

[Jere]

[Rusty666]

cool post

[collaredgirl65]

cool

[Dynamo47]

Very cool. That child in the 3rd photo had some amazing eyes!

[MorbidBabe]

I grew up with a guy that has this he had two brown eyes but half of one eye was blue

[foldingstars]

i went to school with a girls who had 2 different colored eyes,i thought it was pretty cool

[Audioguru]

[Froctopus]

It also happens in ferrets, I have one now that is deaf and another that passed about a year ago from age that had it. Ferrets get it due to breeders breeding for a certain color and pattern. Both of my waardenburg ferrets are/were suuuper sweet too.

Ok found some pics of them:



White chest and stripe on head.




He wore a collar with a bell so we could find him whenever he was out and about since he could not hear us.




Her stripe is a bit thinner, but it's there!






Not sure if white tipped paws are indicative of Waardenburg's for ferrets but they both had them. Oh, and they both had a ruby tint to their eyes as well. Not the red from the camera flash, but if you hold them up and look into their eyes you can see the ruby color in the back.

And a head stomp pic for the hell of it.

[Darkest Angel]

cool. i like the dark hair white streak look (like Rogue in x-men)