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Toxic Epidermal Necrosis Strike

Toxic Epidermal Necrosis Strike 

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  #1  
01-27-2012, 02:35 AM
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Toxic Epidermal Necrosis Strike

I have seen the face (and ass) of pharmacological torture and its name is Toxic Epidermal Necrosis (TEN). This unspeakably foul dermatological condition is induced by a severe reaction to medication (most commonly antibiotics, anti-inflammatories, anti-convulsants, and corticosteroids) and is characterized by the detachment of the top layer of the skin (the epidermis) from the lower layers all over the body. Just think about how that must feel: your entire body, including your mouth, guts, and lips, is shedding its skin.

The initial symptoms of TEN are similar to an upper respiratory infection: malaise, rash, fever, cough, arthralgia, myalgia, rhinitis, headache, anorexia, and nausea and vomiting, with or without diarrhea. When the rash forms, it covers large segments of the body. Within hours, the skin takes on the appearance of a severe burn, with blisters forming and the epidermis beginning to peel away from the underlying tissues. Mucous membranes, such as the mouth, throat, digestive tract, along with genitals and eyes may be severely effected. The mouth becomes blistered and eroded, making eating difficult and sometimes necessitating feeding through a nasogastric tube through the nose or a gastric tube directly into the stomach. The eyes become swollen, crusted, and ulcerated.

Treatment for TEN consists of keeping the patient warm and applying constant hydration via IV, eye irrigation and hydrotherapy. Necrotic areas of the skin are debrided and physical therapy is provided to keep the range of motion intact. A variety of ointments are applied to the skin during the course of the disease, and, of course, lots of opiates are given to the patients to help them weather the excrutiating pain.

Considering how important your skin is to your general well-being, it's not surprising that TEN has a 30-40% mortality rate. What's more surprising to me is that 60-70% of the afflicted actually survive! The severe symptoms of TEN usually last 8-12 days, but it may take up to 3-6 weeks to fully recover. In most cases, survivors do not show any scarring when the epidermis grows back, but in 88% of the cases, there are some disturbances in skin pigmentation.
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  #2  
01-27-2012, 05:24 AM
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Re: Toxic Epidermal Necrosis Strike

Now THAT is a fun looking illness to have, huh.
  #3  
01-27-2012, 06:43 AM
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Re: Toxic Epidermal Necrosis Strike

Oh shit, that would be awful
  #4  
01-27-2012, 07:25 AM
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Re: Toxic Epidermal Necrosis Strike

  #5  
01-27-2012, 08:15 AM
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Re: Toxic Epidermal Necrosis Strike

Great pics and information. Damn that makes me cringe to see that poor babies hand blistered and peeling.
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  #6  
01-27-2012, 11:43 AM
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Re: Toxic Epidermal Necrosis Strike

someone isn't gonna get laid
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  #7  
01-27-2012, 12:59 PM
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Re: Toxic Epidermal Necrosis Strike

That's a bastard of a condition to have
  #8  
01-27-2012, 02:34 PM
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Re: Toxic Epidermal Necrosis Strike

yeeesh
  #9  
01-28-2012, 04:29 AM
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Re: Toxic Epidermal Necrosis Strike

Look..they're turning into zombies..
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  #10  
01-28-2012, 08:10 AM
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Re: Toxic Epidermal Necrosis Strike

You can actually survive this? Wow!


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