[cheekymarls]

Fabry disease is an uncommon, X-linked lysosomal storage disorder, caused by partial or complete deficiency of the enzyme a-galactosidase A. The defect leads to accumulation of uncleaved globotriaosylceramide on the vascular endothelium and visceral tissues, being the skin, heart, kidneys and central nervous system the most affected organs. We performed review of the literature related to the disease and emphasized that early recognition of angiokeratomas and hypohidrosis are key diagnostic signs of this serious disease. We also addressed the need of multidisciplinary assessment of these patients.

Keywords: Alpha-galactosidase; Angiokeratoma; Fabry disease

[vagabond]

Originally Posted by diamondsmiles ↗

I forget who doesn't like people in bath tubs. I think vagabound or teacherof2.

I like all rotting flesh, doesn't matter where!

[DiamondSmiles]

Originally Posted by LadyCPlum ↗

My niece has what's known as "closed" spina bifida.....but there's really nothing wrong with her...she took a bit longer to potty train, sher's got little twigs for legs, and she does have some problems with silly things like making shapes and coloring inside the lines, but other than that she's one of the smartest little squirts on the planet. And a star player on her little peewee soccer team!

Never heard of it, but, good for her!

Who wants to color inside the lines anyway? Make your own lines, Sher!

[DiamondSmiles]

Originally Posted by cheekymarls ↗

Fabry disease is an uncommon, X-linked lysosomal storage disorder, caused by partial or complete deficiency of the enzyme a-galactosidase A. The defect leads to accumulation of uncleaved globotriaosylceramide on the vascular endothelium and visceral tissues, being the skin, heart, kidneys and central nervous system the most affected organs. We performed review of the literature related to the disease and emphasized that early recognition of angiokeratomas and hypohidrosis are key diagnostic signs of this serious disease. We also addressed the need of multidisciplinary assessment of these patients.

Keywords: Alpha-galactosidase; Angiokeratoma; Fabry disease

Well, that didn't go well with my Frosty! (Like a thick milkshake, if you don't have Wendy's there. I freeze mine anyway.)

[DiamondSmiles]

Originally Posted by LadyCPlum ↗

What the Hell IS THAT???????????????????????

It's E.T.'s autopsy of the brain, you idiot!

[DiamondSmiles]

Originally Posted by cheekymarls ↗

awww
I think no one is born perfect, but are perfect in our eyes

What some people see as, "flaws," are what can make them unique.

I get teary eyed when I see someone who was paralyzed walk, or the toddlers who hear and see for the first time.

They had a bride on the news a few days ago walk down the aisle and her husband to be didn't know she was going to do it. I lost it! He carried her back to her chair after they were married.

I cry when military personnel are reunited with their children or mothers. Priceless moments!

[DiamondSmiles]

Originally Posted by LadyCPlum ↗

This looks like the condition my little cousin Jay died from. My aunt was induced at 7 months because she had a HUGE amount of amniotic fluid, plus the ultrasounds were showing no limb growth whatsoever. He only lived for a few hours. I never got to meet him. But I tell my aunt, uncle, and his two sisters to always remember they have a Guardian Angel looking out for all of them.

I'm sorry for your and your family's loss. xx

[DiamondSmiles]

Anthrax

Chicken Pox

Flesh Eating Disease

Trichotillomania

Flesh Eating Disease

[DiamondSmiles]

Originally Posted by vagabond ↗

I like all rotting flesh, doesn't matter where!

Hmmm...Maybe it's Anom Alley then. I know it's one of the ladies. Too many posts to reread. I tried.

[cheekymarls]

Originally Posted by diamondsmiles ↗

What some people see as, "flaws," are what can make them unique.

I get teary eyed when I see someone who was paralyzed walk, or the toddlers who hear and see for the first time.

They had a bride on the news a few days ago walk down the aisle and her husband to be didn't know she was going to do it. I lost it! He carried her back to her chair after they were married.

I cry when military personnel are reunited with their children or mothers. Priceless moments!

my tears swelled up reading that... very touching