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10-27-2014, 11:25 AM
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Phaeohyphomycosis
Phaeohyphomycosis Description: A mycotic infection of humans and lower animals caused by a number of dematiaceous (brown-pigmented) fungi where the tissue morphology of the causative organism is mycelial. This separates it from other clinical types of disease involving brown-pigmented fungi where the tissue morphology of the organism is a grain (mycotic mycetoma) or sclerotic body (chromoblastomycosis). The etiological agents include various dematiaceous hyphomycetes especially species of Exophiala, Phialophora, Wangiella, Bipolaris, Exserohilum, Cladophialophora , Phaeoannellomyces, Aureobasidium, Cladosporium, Curvularia and Alternaria. Ajello (1986) listed 71 species from 39 genera as causative agents of phaeohyphomycosis. Clinical manifestations: Clinical forms of phaeohyphomycosis range from localized superficial infections of the stratum corneum (tinea *****) to subcutaneous cysts (phaeomycotic cyst) to invasion of the brain. Ideally, individual disease states involving an invasive fungal infection by a dematiaceous hyphomycete should be designated by a specific description of the pathology and the causative fungal genus or species (where known); for example "pathology A" caused by "fungus X". |