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#1
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07-04-2024, 06:14 PM
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 These are the rooms Poster Rank:25 of ruin. Join Date: Sep 2014 Posts: 54,011 Mentioned: 145 Post(s) Quoted: 30403 Post(s)
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Neurofibromatosis
A 64-year-old lady with underlying neurofibromatosis presented with back swelling for the past five years. The swelling was painless, and it had rapidly increased in size for the past year with ulceration. She denied any fever; however, the ulcer was foul-smelling and associated with on-and-off pus discharge. However, she sought treatment for this problem multiple times and received antibiotics. She was treated for infected neurofibromatosis by a general practitioner. Due to an unresolved infection, she was referred to a tertiary center for further management. Upon review by the orthopedic team, there was a huge mass on her back with necrotic skin (Figures 1-2). The surrounding skin was erythema, and it was hard in consistency. She underwent a wide local excision of the mass. The intraoperative finding was an ulcerated soft tissue tumor measuring about 15 cm x 20 cm at the posterior trunk with central hemorrhagic necrosis (Figures 3-5). The mass is attached to the fascia and some parts of the erector spinae muscle. The mass was sent for histopathology examination (HPE). The HPE came back with a malignant peripheral nerve sheath tumor. Computed tomography (CT) scan of the thoracic, abdominal, and pelvis (TAP) showed multiple lung nodules and lytic bone lesions. She underwent adjuvant radiotherapy after surgery. She was doing well after surgery, as she was able to lie flat. Figure 6 shows her back condition two weeks after surgery. After six months of serial follow-up in the clinic, there was no sign of recurrent tumors.
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#2
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07-04-2024, 07:18 PM
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 ♚ Legacy Gold Member ♚ Poster Rank:267 ꓕSIꓤIꓕ∀S ϽINOᗡꓤ∀S Join Date: Feb 2010 Posts: 5,102
Contributions: 6
Mentioned: 38 Post(s) Quoted: 1417 Post(s)
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Re: Neurofibromatosis
I'm sometimes gobstruck when I see massive infected tumors with tissue necrosis that go virtually untreated for years without the patient succumbing to sepsis. As an aside though, modern dermatology has advancing treatments for many types of neurofibromatosis. A procedure using electrodesiccation and curettage can mostly dry up and remove those benign tumors on her skin, leading to a very improved quality of life. Here's an example photo... 
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#6
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07-05-2024, 03:53 AM
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 ★ Legacy Member ★ Poster Rank:119 Secret Agent Join Date: Dec 2009 Posts: 13,214 Mentioned: 6 Post(s) Quoted: 2789 Post(s)
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Re: Neurofibromatosis
If you zoom in a little on her back it looks like an alien planet landscape.  |
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#8
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07-05-2024, 09:15 AM
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 ♚ Legacy Gold Member ♚ Poster Rank:1280 Femme fatale Join Date: May 2024 Posts: 477 Mentioned: 1 Post(s) Quoted: 191 Post(s)
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Re: Neurofibromatosis
I would not be able to handle having all those weird lumps and bumps on my back.
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