[DiamondSmiles]

[Ghost306]

Sad condition.

[GODREKR]

From Wikipedia:

Xeroderma pigmentosum, or XP, is an autosomal recessive genetic disorder of DNA repair in which the ability to repair damage caused by ultraviolet (UV) light is deficient. In extreme cases, all exposure to sunlight must be forbidden, no matter how small; as such, individuals with the disease are often colloquially referred to as Children of the Night. Multiple basal cell carcinomas (basaliomas) and other skin malignancies frequently occur at a young age in those with XP. In fact, metastatic malignant melanoma and squamous cell carcinoma are the two most common causes of death in XP victims. This disease involves both sexes and all races, with an incidence of 1:250,000 in the United States and a gene frequency of 1:200. XP is roughly six times more common in Japanese people than in other groups.

Normally, damage to DNA in epidermal cells occurs during exposure to UV light. The absorption of the high energy light leads to the formation of pyrimidine dimers, namely cyclobutane-pyrimidine dimers and pyrimidine-6-4-pyrimidone photoproducts. In a healthy, normal human being, the damage is first excised by endonucleases. DNA polymerase then repairs the missing sequence, and ligase "seals" the transaction. This process is known as nucleotide excision repair.

Xeroderma pigmentosum

More info here, here, and here.

[DiamondSmiles]

Wow! Thank you so much, GODREKR!

Stupid parents should keep their children out of the sun!

If they want to do it, that is one thing, but, to destroy the children is just crazy!

[LadyCPlum]

This is why I like to sstay as far away from the sun as possible. Thanks to my milk-white skin and rather decent amount of moles, I wouldn't want to chance anything!

[DiamondSmiles]

Originally Posted by LadyCPlum ↗

This is why I like to sstay as far away from the sun as possible. Thanks to my milk-white skin and rather decent amount of moles, I wouldn't want to chance anything!

Me, too! I like glowing in the dark and having soft skin.

[LadyCPlum]

Originally Posted by diamondsmiles ↗

Me, too! I like glowing in the dark and having soft skin.

Hell I'm so white I think I actually reflect the sun's rays, and I burn incredibly easy too! That reminds me of a time when I was in the restroom at work and a friend of mine, who's black, came out of the stall while we were washing our hands, and I had on a strappy shirt. She goes "Damn girl, you are so WHITE!" I just had to get her back. "Hang on Tonya, how would you feel if someone came up and said 'Damn girl, you are so black!'?" She completely lost it.

My mother, father, maternal grandmother, paternal grandfather, and brother have all been diagnosed with skin cancer at some point. All of us are just covered with freckles and moles....my father was a mailman, and he had a walking route, which meant hours in the sun. He slathered on the Bullfrog and wore his little Panama hat, and he still has had to have several moles removed. My grandfather actually had skin cancer in his esophagus, of all places! My mother and grandmother have had to have cancerous growths removed from their noses, etc., etc. I figure I'd rather stay Goth-pale and not look like a piece of burnt turkey jerky and creak like a cracked belt when I walk, like so many people who tan and spend half the day in the sun do. Strange thing is, I frigging smoke, (irony, irony, irony) and when I'm in my car I usuall hang my left arm out the window, and from being exposed to the sun so often, that one arm is darker than the rest of my body!

[kustom80]

Originally Posted by GODREKR ↗

From Wikipedia:

Xeroderma pigmentosum, or XP, is an autosomal recessive genetic disorder of DNA repair in which the ability to repair damage caused by ultraviolet (UV) light is deficient. In extreme cases, all exposure to sunlight must be forbidden, no matter how small; as such, individuals with the disease are often colloquially referred to as Children of the Night. Multiple basal cell carcinomas (basaliomas) and other skin malignancies frequently occur at a young age in those with XP. In fact, metastatic malignant melanoma and squamous cell carcinoma are the two most common causes of death in XP victims. This disease involves both sexes and all races, with an incidence of 1:250,000 in the United States and a gene frequency of 1:200. XP is roughly six times more common in Japanese people than in other groups.

Normally, damage to DNA in epidermal cells occurs during exposure to UV light. The absorption of the high energy light leads to the formation of pyrimidine dimers, namely cyclobutane-pyrimidine dimers and pyrimidine-6-4-pyrimidone photoproducts. In a healthy, normal human being, the damage is first excised by endonucleases. DNA polymerase then repairs the missing sequence, and ligase "seals" the transaction. This process is known as nucleotide excision repair.

Xeroderma pigmentosum

More info here, here, and here.

That first picture

[murofhsirgo]

that is terrible.
guy in first pic- compounded by a full beard to shave:(

[DiamondSmiles]

Originally Posted by LadyCPlum ↗

Hell I'm so white I think I actually reflect the sun's rays, and I burn incredibly easy too! That reminds me of a time when I was in the restroom at work and a friend of mine, who's black, came out of the stall while we were washing our hands, and I had on a strappy shirt. She goes "Damn girl, you are so WHITE!" I just had to get her back. "Hang on Tonya, how would you feel if someone came up and said 'Damn girl, you are so black!'?" She completely lost it.

My mother, father, maternal grandmother, paternal grandfather, and brother have all been diagnosed with skin cancer at some point. All of us are just covered with freckles and moles....my father was a mailman, and he had a walking route, which meant hours in the sun. He slathered on the Bullfrog and wore his little Panama hat, and he still has had to have several moles removed. My grandfather actually had skin cancer in his esophagus, of all places! My mother and grandmother have had to have cancerous growths removed from their noses, etc., etc. I figure I'd rather stay Goth-pale and not look like a piece of burnt turkey jerky and creak like a cracked belt when I walk, like so many people who tan and spend half the day in the sun do. Strange thing is, I frigging smoke, (irony, irony, irony) and when I'm in my car I usuall hang my left arm out the window, and from being exposed to the sun so often, that one arm is darker than the rest of my body!

I'm Casper white and if people don't like it, I blind them!

I prefer the beach at night anyway.

Did you see the video of the truck driver whose left side of his face looked years older than his right because of the sun hitting it?

I have what I call, a playground tan, from the last few days of school with my niece.

I had on a visor and sunblock, but, one spot on my face and the area below my neck got hit a bit.

My scalp got sunburned, too, so I now have the stuff you put on babies' heads, in case I have to be in the sun again.

I wore a visor instead of a cap because I hate hates!

She was having such a great time and I thought I was covered enough. My lower arms are a bit tan, too.

I can tan. I choose not to do so. Prevention is easier than correction.

I thought all women were soft all over, but, men have told me differently, and I like that. I like them to have soft skin and be well-groomed, too.

Fair is fair!

I posted something else about sun on here.