|
#12
●
07-21-2016, 05:30 PM
|
|
Re: Largest Bladder Stone Ever
A bit of info from a doggy page: Normal dog urine is slightly acidic and contains waste products from metabolism including dissolved mineral salts and other compounds. Struvite is a normal component of dog's urine and will remain dissolved as long as the urine is acidic and is not too concentrated. If the urine becomes exceptionally concentrated or if it becomes alkaline, struvite crystals will precipitate or fall out of solution. In dogs, struvite bladder stones usually form as a complication of a bladder infection caused by bacteria that produce an enzyme known as urease. This enzyme breaks down the urea that is normally present in the urine causing an excess production of ammonia; this ammonia production then causes the urine to become alkaline. Ammonia in the urine also causes bladder inflammation. Under these environmental conditions, struvite crystals will precipitate out of solution and collect around any cells or debris that may have formed in the bladder as a result of inflammation. Female dogs tend to get these types of bladder infections and stones much more frequently than males, probably because their shorter, wider urethra makes it easier for bacteria to pass up the urethra into the bladder. In some studies, up to 85% of dogs with struvite bladder stones were female. Other causes of alkaline urine such as certain kidney diseases, long-term use of diuretic drugs or antacids, and other conditions that cause elevated urine pH or elevated levels of urinary phosphorus or ammonia can also predispose a dog to the formation of struvite bladder stones. |