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Alobar Holoprosencephaly

Alobar Holoprosencephaly

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  #1  
● 07-12-2024, 03:57 PM
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Alobar Holoprosencephaly

A 29-year-old female G1P1 presented to the Obstetrics and Gynecology Department with a sudden absence of in-pregnancy symptoms such as pregnancy craving, vomiting, and nausea, accompanied by lower abdominal pain and mild spotting. There were no other symptoms. The mother had a partus caesarius 2 years ago. The mother had smoked three packs per year for 6 years. There was no other medical, family, surgical, or allergic history. The mother was at 12+2 weeks gestation based on her last menstrual cycle and had never had an US before during this pregnancy.

The US demonstrated a non- viable intrauterine fetus at age 11 weeks gestation, with irregularities in the skull bones and severe cerebral malformation. A single orbital cave was also noted. The US investigation was ineffective. 800 mg of Misoprostol was prescribed to induce medical miscarriage (400 mg oral and 400 mg vaginal).

The pathological exam demonstrated a male embryo measuring 7 cm in length (Figure 1). Gross examination showed a single central orbit located in the middle of the face with a cutaneous horn above it (Figure 2); and poly-dactyly in its left foot, attached with a normal umbilical cord (Figure 3). The visceral organs of the embryo were normal except the brain's front, which showed adhesion of its right and left hemispheres. A placenta measures 7 × 2 cm and is composed of normal villi and decidual tissue (Figure 1).
Alobar Holoprosencephaly - RDT 20240712 1254274451740956684710940
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Alobar Holoprosencephaly - RDT 20240712 1254336419952506548693175
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Alobar Holoprosencephaly - RDT 20240712 125439731061813065343941
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  #2  
● 07-12-2024, 04:02 PM
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Re: Alobar Holoprosencephaly

Damn.















That placenta is frigging huge!
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  #3  
● 07-12-2024, 04:39 PM
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Re: Alobar Holoprosencephaly

Neat
  #4  
● 07-13-2024, 12:02 AM
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Re: Alobar Holoprosencephaly

So scary looking!

Is he laying on a cutting board?
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  #5  
● 07-13-2024, 03:40 AM
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Re: Alobar Holoprosencephaly

Cyclops ~
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  #6  
● 07-13-2024, 04:48 AM
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Re: Alobar Holoprosencephaly

The placenta looks like a flayed face spewing chunks, in the 2nd Pic, my first thought with the 1 eye and horn was antichrist. I'm going to get struck by lightning now
  #7  
● 07-13-2024, 06:11 PM
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Re: Alobar Holoprosencephaly

Was it going to be a cyclops?
If so, Mother Nature did that job..ending it I mean. Because I feel like that isn’t a quality of life.
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