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#1
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06-21-2009, 03:33 AM
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Radiation Burns
Image 01 Radiation skin burn with skin islands on the left leg of patient D (1 February 1963). Image 02 Radiation skin burn on both knees of patient D (1 February 1963). Image 03 Extensive radiation skin burn with slough and ulcer on the buttocks of patient A (11 February 1963). Image 04 Radiation skin burn on both legs, more on the left side, of patient D (1 February 1963). -Hey Zeus Guevara- |
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#2
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06-21-2009, 03:40 AM
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Re: Radiation Burns
Abstract Info: In 1963, six cases of acute radiation sickness resulting from an accidental non-uniform 60Co -ray irradiation of approximately 10 Ci were treated first in Hefei, Anhui province, and were then transferred to our hospital. The whole body average doses were estimated to be 2 x 102 cGy to 8 x 103 cGy. Two of patients died of intestinal acute radiation sickness within 2 weeks. Autopsy findings revealed findings consistent with multi-organ failure. Four cases survived, and one of them recovered from septicaemic shock. Loss of hair, systemic infection, high fever and bleeding occurred in five cases. The essential therapeutic measures were strict isolation, preventive treatment with anti-infection drugs, fresh blood transfusion and sometimes infusion of formed blood elements. Among the survivors, two cases received homologous bone marrow transfusion. The general conditions of four cases followed-up for a period of 24–40 years are apparently good, with transparent lens, normal thyroid function and normal immunological reactions, except one patient who had a low serum immunoglobulin G level. Three cases showed subnormal adrenocortical activity and impairment of sex gland function. Patient A died from a car accident 24 years after the radiation accident. Patient C gave birth to a daughter and a son; the latter had severe mental retardation. Serial electroencephalographic changes occurred only in those cases who received high cranial doses. In all the cases, persistence of chromosome aberrations in peripheral lymphocytes was observed. Owing to local high doses, the remote regional effects led to amputation of one leg in patient D and to pathological fracture of the femur in patient A. Brief account of the accident: On 11 January 1963, a 60Co -ray source of approximately 10 Ci used for irradiation of seeds was taken by a rural child to his home. Six people were exposed to an accidental non-uniform -ray irradiation; five of them for a period of 5–9 days (the child's mother, two brothers, a sister and himself), and another person, the child's uncle who happened to stay at their home overnight, for 9 h. The -ray irradiation from the 60Co source resulted in acute radiation sickness of all six persons, accompanied by different degrees of localised radiation injury. |