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Pemphigus Vulgaris

Pemphigus Vulgaris 

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  #1  
01-13-2013, 03:06 PM
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Pemphigus Vulgaris



A localized form of pemphigus vulgaris, the autoimmune disease which causes antibodies to attack the proteins desmoglein 1 and desmoglein 3. The destruction of these proteins causes the loss of cohesion between keratinocytes within the epidermis, leading to easily rupturing blisters in patients. Though the keratinocytes are not attached to each other, they’re often attached to the basement membrane, which can lead to “tombstoning.”
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  #2  
01-13-2013, 03:15 PM
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Re: Pemphigus Vulgaris

Oh that's awful
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  #3  
01-13-2013, 03:19 PM
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Re: Pemphigus Vulgaris

Yuck, yuck, yuck! Fuckin' A, that sucks!
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  #4  
01-13-2013, 03:20 PM
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Re: Pemphigus Vulgaris

wow how would you like to wake up to that scary fucker after a drunk evening
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  #5  
01-13-2013, 03:39 PM
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Re: Pemphigus Vulgaris

poor old guy.
Kids and old folk get me every time.
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  #6  
01-13-2013, 07:52 PM
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Re: Pemphigus Vulgaris

Poor guy I wonder if it's painful
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  #7  
01-13-2013, 09:40 PM
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Re: Pemphigus Vulgaris

Though the keratinocytes are not attached to each other, they’re often attached to the basement membrane, which can lead to “tombstoning.”

that would lead me to whole body tombstoning - 6 feet under. i'd probably kill myself if i had that.
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  #8  
01-13-2013, 09:57 PM
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Re: Pemphigus Vulgaris

Zombie disease.
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  #9  
01-13-2013, 10:24 PM
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Re: Pemphigus Vulgaris

What a horrible thing to have. You know he is completely miserable !
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  #10  
01-14-2013, 12:59 PM
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Re: Pemphigus Vulgaris

No end to these horrible medical conditions. One time I looked up "syndromes" to learn a little about each, and was horrified to find hundreds of them listed. Couldn't even put a dent in them.
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