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12-10-2009, 05:21 PM
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 My Rank: PRIVATE FIRST CLASS Poster Rank:3580 Join Date: Oct 2009 Posts: 96 Mentioned: 0 Post(s) Quoted: 2 Post(s)
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Children With Toxic Epidermal Necrolysis
Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a life-threatening dermatological condition that is frequently induced by a reaction to medications. It is characterized by the detachment of the top layer of skin (the epidermis) from the lower layers of the skin (the dermis) all over the body. The incidence is between 0.4 and 1.2 cases per million each year. Microscopically, TEN causes cell death throughout the epidermis. Keratinocytes, which are the cells found lower in the epidermis, specializing in holding the skin cells together, undergo necrosis (cell death).    Worst of all TEN affects many parts of the body, but it most severely affects the mucous membranes, such as the mouth, eyes, and vagina. |
PAIN!!! 
